Trials 2019; 20: 142, ISBN 1745-6215 (Journal)
Speich Benjamin, Bausch Kathrin, Roth Jan A., Hemkens Lars G., Ewald Hannah, Vogt Deborah R., Bruni Nicole, Deuster Stefanie, Seifert Hans-H., Widmer Andreas F.
Transurethral resection of the prostate (TURP) and Greenlight laser vaporisation (GL) of the prostate are frequently performed urological procedures. For TURP, a single-dose antimicrobial prophylaxis (AP) is recommended to reduce postoperative urinary tract infections. So far, no international recommendations for AP have been established for GL. In a survey-based study in Switzerland, Germany and Austria, urologists reported routinely extending AP primarily for 3 days after both interventions. We therefore aim to determine whether single-dose AP with cotrimoxazole is non-inferior to 3-day AP with cotrimoxazole in patients undergoing TURP or GL of the prostate.