DISCO - Reporting of discontinued trials DISCO 2

Matthias Briel, Kelechi Kalu Olu, Stefan Schandelmaier

Status: Abgeschlossen Dauer: Jan. 2013 - Juli 2016

The objectives of this empirical study are (i) to gather a comprehensive list of published root causes for RCT discontinuation due to poor recruitment, (ii) to examine to what extent and how investigators of RCTs discontinued due to poor recruitment report results and lessons learned, and (iii) to investigate the proportion of actually recruited patients in relation to the target sample size in RCTs discontinued due to poor recruitment. We will use 3 different approaches in order to identify RCT publications of RCTs discontinued due to poor recruitment: (1) subsample from the DISCO study; (2) search using the Medical Subject Heading (MeSH) term discontinued trial; and (3) a text word search

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