SHCS 805 Drug-in Drug Interactions

Prof. Heiner C. Bucher

Status: Abgeschlossen Dauer: Okt. 2016 - Dez. 2018

Potential drug-drug interactions (DDI) are the most common drug-related problem in ambulatory care and a growing problem in HIV infection due to increasing comorbidities and age of HIV-infected patients. In this study of the Swiss HIV Cohort Study (SHCS) we assess the prevalence of contraindicated and potential clinically relevant DDIs and determine major patients and provider related predictors of DDIs in patients receiving antiretroviral therapy. Finally we validate drug data entered into the new Webmed database of the SHCS with a probability matched patient sample of claim data of Helsana, the largest Swiss health insurer. \n\n

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